Dr. Luc Berghman was recognized for his accomplishments during the 2019 Patent and Innovations Award Luncheon which was held on Thursday, April 18, 2019 at the Annenberg Presidential Conference Center. This event was put on by the Texas A&M University System Office of Technology Commercialization and spotlights the patents and PVP’s issued to TAMU faculty during 2018.
Patents issued to Dr. Berghman in 2018 include:
- 3437AGLR11-07, COMPOSITIONS AND METHODS OF ENHANCING IMMUNE RESPONSES TO EIMERIA OR LIMITING EIMERIA, Patent #9,884,099, Issued 2/6/2018
- 3054AGLR10-04, VACCINE VECTORS AND METHODS OF ENHANCING IMMUNE RESPONSES, Patent # 9,913,893, Issued 3/13/2018
- 2420AGLR06-08 ,COMPOSITIONS AND METHODS OF ENHANCING IMMUNE RESPONSES, Patent # 10,004,798, Issued 6/26/2018
- 4233AGLR15-12, COMPOSITIONS AND METHODS OF ENHANCING IMMUNE RESPONSES TO EIMERIA, Patent # 10,016,493, Issued 7/10/2018
These patents cover inventions that enhance the immunoprotective capacity of bacterial vaccine vectors, including one that forms the core of a coccidiosis vaccine. One enhancement consists of the co-expression of Danger Associated Molecular Patterns (DAMPs) on the bacterial vector. Recognition of a DAMP results in vigorous activation of the host’s innate immune system. Another improvement consists of also expressing a chicken CD40-binding molecule on the vector, which jumpstarts the Antigen-Presenting Cells (APCs) in the host, yielding stronger, faster, and longer lasting immune responses.
Congratulations Dr. Berghman!